Salves are best for targeting specific, topical areas in need of instant relief. When you apply our beeswax-based salve, the CBD penetrates transdermally, avoiding first-pass metabolism through the gastrointestinal tract and increasing the bioavailability of the CBD. As opposed to our Roll-On, which is aqua-based, the beeswax base allows for a steady infusion over a prolonged period of time.